CT scans of these organs involve two different examination methods, depending on the indications. The first group of indications includes examinations performed without the use of contrast agents, aimed at assessing bone structure in Paget’s disease, fibrous dysplasia, post-traumatic changes or osteoarthritis of the large joints, where the clinical and radiological picture is inconclusive on a standard X-ray. The second group of indications, in addition to the assessment of bone structures, covers soft-tissue pathologies surrounding the bone, as well as inflammatory and neoplastic infiltrates spreading from bone to soft tissues or vice versa. Indications include benign and malignant tumours of the bones and joints, assessment of the extent of neoplastic infiltrates and their relationship to the bone marrow cavity and soft tissues, as well as chronic and atypical inflammatory conditions of the bones and joints. In these cases, the administration of a contrast agent is necessary – the patient should fast beforehand. Multi-detector CT systems, in addition to enabling a detailed assessment of complex fractures (thin slices, retro-reconstructions and 3D), are also capable of visualising even soft tissues, such as cruciate ligaments, with high quality – for which magnetic resonance imaging is the examination of choice. Furthermore, modern software allows images from different cross-sectional levels of the limb to be superimposed on one another to calculate angles, such as anteversion, or other parameters useful for planning orthopaedic procedures.